Fildena 100 is a widely recognized medication for treating erectile dysfunction (ED) in men, and its effectiveness is grounded in solid science. The active ingredient in Fildena 100 is Sildenafil Citrate, a potent phosphodiesterase type 5 (PDE5) inhibitor. Understanding how this medication works involves a closer look at the physiological processes involved in achieving an erection.
Mechanism of Action
Role of PDE5 Enzyme:
PDE5 is an enzyme that regulates blood flow in the penis. Normally, after sexual stimulation, the body releases nitric oxide (NO), which triggers the production of cyclic guanosine monophosphate (cGMP). cGMP relaxes the smooth muscle tissues in the blood vessels of the penis, allowing increased blood flow, leading to an erection.
PDE5 breaks down cGMP, which can cause the erection to subside. In men with ED, PDE5 may be overly active, leading to insufficient cGMP levels and difficulties in maintaining an erection.
Inhibition of PDE5:
Fildena 100, through Sildenafil Citrate, inhibits the action of PDE5. By blocking this enzyme, Fildena 100 prevents the breakdown of cGMP, allowing it to accumulate and persist longer. This results in prolonged relaxation of the blood vessels in the penis, thereby enhancing blood flow and facilitating a strong and sustained erection.
Sexual Stimulation:
It’s important to note that Fildena 100 requires sexual arousal to be effective. The medication does not initiate an erection on its own but enhances the body’s natural response to sexual stimulation.
Duration and Onset of Action
Locked
