Bioglandin Injection, containing the active ingredient alprostadil, is primarily used to treat erectile dysfunction (ED) and patent ductus arteriosus (PDA) in newborns. Understanding potential drug interactions is crucial to ensure safe and effective use.
Drug Interactions:
Alprostadil may interact with several medications, potentially altering their effects or increasing the risk of side effects. Notable interactions include:
Sildenafil (Viagra): Combining alprostadil with sildenafil can lead to increased side effects such as headaches, dizziness, and changes in heart rate. It's essential to consult your healthcare provider before using these medications together.
Minoxidil: This combination may require dose adjustments and close monitoring due to potential interactions. Report any symptoms like fainting, drowsiness, or changes in heart rate to your doctor.
Sodium Nitrite: Using
Bioglandin Injection with sodium nitrite necessitates careful clinical monitoring to manage the risk of excessive blood pressure reduction.
Riociguat: This combination may require dose adjustments and close monitoring due to potential interactions.
Additionally, alprostadil has known interactions with 43 other medications, including hydralazine, empagliflozin, and sildenafil. It's important to review all current medications with your healthcare provider to identify and manage potential interactions.
Disease Interactions:
Alprostadil may have interactions with certain diseases, including respiratory function, bleeding disorders, and hypotension. Discuss your medical history with your healthcare provider to ensure alprostadil is safe for you.
Alcohol Interaction:
The interaction between alprostadil and alcohol is unknown. It's advisable to consult your doctor before consuming alcohol while using this medication.
Consulting Your Healthcare Provider:
Before starting alprostadil, inform your healthcare provider about all medications, including over-the-counter drugs, supplements, and herbal products. This information is vital for assessing potential interactions and determining the appropriate treatment plan.
For comprehensive information on alprostadil's interactions, refer to the Drugs.com interaction checker.
Always follow your healthcare provider's guidance regarding the use of alprostadil and any other medications to ensure safety and efficacy.
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